Prasad

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All Publications

  1. Dhurjati, P., D. Ramkrishna, M. C. Flickinger and G. T. Tsao, "Cybernetic Modeling of Microbial Growth in Multiple Substrate Systems", Proc. Sec. World Cong. Chem. Eng., 16 (5), 252-255 (1981)

  2. Chester, D. L., D. E. Lamb and P. Dhurjati, "An Expert System Approach to On-Line- Alarm Analysis in Power and Process Plants", Computers in Engineering, 1, 345-351 (1984)

  3. Chester, D. L., D. E. Lamb and P. Dhurjati, "Rule-Based Computer Alarm Analysis in Chemical Process Plants", Microdelcon, 1, 22-29 (1984)

  4. Dhurjati, P., D. Ramkrishna, M. C. Flickinger and G. T. Tsao, "A Cybernetic View of Microbial Growth: Modeling of Cells as Optimal Strategists", Biotechnology and Bioengineering, 27, 1-9 (1985)

  5. Givler, R. M., P. Dhurjati and M. T. Klein, "A Model Compound Analysis of a Strategy for the Selective Microbial Pretreatment of Lignin", The Chemical Engineering Journal, 30, B37-B41 (1985)

  6. Lamb, D. E., P. Dhurjati and D. L. Chester, "Development of an Expert System for Fault Identification in a Commercial Scale Chemical Process", Proc. Sixth Int. Workshop on Expert Systems and Their Applications, Avignon, 2, 1371-1382 (1986)

  7. Hopkins, D. J., M. J. Betenbaugh and P. Dhurjati, "Effects of Dissolved Oxygen Shock on the Stability of Recombinant Escherichia coli Containing Plasmid pKN401", Biotechnology and Bioengineering, 29, 85-91 (1987)

  8. Pih, N. and P. Dhurjati, "Oscillatory Behavior of beta-galactosidase Enzyme Activity in Escherichia coli during Perturbed Batch Experiments", Biotechnology and Bioengineering, 29, 292-296 (1987)

  9. DiPasquantonio, V. M., M. J. Betenbaugh and P. Dhurjati, "Improvement of Product Yields by Temperature Shifting of Escherichia coli Cultures Containing Plasmid pOU140", Biotechnology and Bioengineering, 29, 513-519 (1987)

  10. DeBernardez, E. and P. Dhurjati, "Effect of a Broad-Host Range Plasmid on the Growth Dynamics of Escherichia coli and Pseudomonas putida", Biotechnology and Bioengineering, 29, 558-565 (1987)

  11. Coppella, S. J., C. M. Acheson and P. Dhurjati, "Measurement of Copy Number Using HPLC", Biotechnology and Bioengineering, 29, 646-647 (1987)

  12. Coppella, S. J. and P. Dhurjati, "Low Cost Computer-Coupled Fermentor Off-Gas Analysis via Quadrupole Mass Spectrometer", Biotechnology and Bioengineering, 29, 679-689 (1987)

  13. Kim, S. U. and P. Dhurjati, "Analysis of Two Interacting Bacterial Populations with Opposite Substrate Preferences", Biotechnology and Bioengineering, 29, 1015-1023 (1987)

  14. Betenbaugh, M. J., V. M. diPasquantonio and P. Dhurjati, "Growth Kinetics of Escherichia coli Containing Temperature-Sensitive Plasmid pOU140", Biotechnology and Bioengineering, 29, 1164-1172 (1987)

  15. Coppella, S. J., C. M. Acheson and P. Dhurjati, "Isolation of High Molecular Weight Nucleic Acids for Copy Number Analysis Using HPLC", Journal of Chromatography, 402, 189-199 (1987)

  16. Dhurjati, P., D. E. Lamb and D. C. Chester, "Experience in the Development of an Expert System for Fault Diagnosis in a Commercial Scale Chemical Process", in Foundations of Computer Aided Process Operations, (Elsevier Science Publishers, New York 1987)

  17. Venkatasubramanian, V. and P. Dhurjati, "An Object-Oriented Knowledge Base Representation for the Expert System FALCON", in Foundations of Computer Aided Process Operations, (Elsevier Science Publishers, New York 1987)

  18. Kim, S. U., D. Kim and P. Dhurjati, "Mathematical Model for the Mixed Culture Growth of Two Bacterial Populations with Opposite Substrate Preferences", Biotechnology and Bioengineering, 31, 144-159 (1988)

  19. Pih, N. P., E. DeBernardez and P. Dhurjati, "Elucidation of Enzyme Control Mechanisms Using Macroscopic Measurements in a Mixed Substrate Fermentation System", Biotechnology and Bioengineering, 31, 311-320 (1988)

  20. DeBernardez, E. D. and P. Dhurjati, "Host-Plasmid Interactions in Gram-Negative Bacteria Harboring Broad-Host Range Plasmids", BioProcess Engineering, 3, 141 (1988)

  21. Bree, M. A., P. Dhurjati, R. F. Geohagen and B. Robnett, "Kinetic Modeling of Hybridoma Cell Growth and Immunoglobulin Production in a Large Scale Suspension Culture", Biotechnology and Bioengineering, 32, 1067-1072 (1988)

  22. Mooney, D. J., D. Chester, D. Lamb and P. Dhurjati, "Design and Operation of the FALCON Interface", Proceedings of ISA, 88, 747-758 (1988)

  23. Coppella, S. J. and P. Dhurjati, "Mathematical Modeling of Cell Growth and Human Epidermal Growth Factor Production in Recombinant Yeast", in Proceedings of the ISMM International Symposium:, (ACTA Press, Anaheim 1988)

  24. Walker, C. C. and P. Dhurjati, "Use of Culture Fluorescence as a sensor for on-line discrimination between recombinant and host Escherichia coli", Biotechnology and Bioengineering, 33, 500-505 (1989)

  25. Betenbaugh, M. J., C. Beaty and P. Dhurjati, "Effects of Plasmid Amplification and Recombinant Gene Expression on the Growth Kinetics of Recombinant E. coli", Biotechnology and Bioengineering, 33, 1425-1436 (1989)

  26. Coppella, S. J. and P. Dhurjati, "Effect of Plasmid Size and Medium on Growth Kinetics and Plasmid Copy Number in Saccharomyces Cerevisiae", BioProcess Engineering, 4, 75-80 (1989)

  27. Coppella, S. J. and P. Dhurjati, "Alpha-Factor Directed Expression of the Human Epidermal Growth Factor in Saccharomyces Cerevisiae", Biotechnology and Bioengineering, 33, 976-983 (1989)

  28. Dhurjati, P. and R. J. Leipold, "Mathematical Modeling of Biological Systems", in Computer Control of Fermentation Processes, edited by Daniel R. Omstead (CRC Press, Boca Raton, FL 1989)

  29. Coppella, S. J. and P. Dhurjati, "A Detailed Analysis of Saccharomyces cerevisiae Growth Kinetics in Batch, Fed Batch, and Hollow Fiber Reactors", The Chemical Engineering Journal, 41, B27-B35 (1989)

  30. Coppella, S. J. and P. Dhurjati, "A Mathematical Description of Recombinant Yeast", Biotechnology and Bioengineering, 35, 356-374 (1990)

  31. Betenbaugh, M. J. and P. Dhurjati, "A Comparison of Mathematical Model Predictions to Experimental Measurements for Growth and Recombinant Protein Production in Induced Cultures of Escherichia coli", Biotechnology and Bioengineering, 36, 124-134 (1990)

  32. LaMarca, C., A. M. Lenhoff and P. Dhurjati, "Partitioning of Host and Recombinant Cells in Aqueous Two-Phase Polymer Systems", Biotechnology and Bioengineering, 36, 484-492 (1990)

  33. Petti, T. F., J. Klein and P. Dhurjati, "The Diagnostic Model Processor -Using Deep Knowledge for Process Fault Diagnosis", AIChE Journal, 36, 565-575 (1990)

  34. Betenbaugh, M. J. and P. Dhurjati, "Effects of Promoter Induction and Copy Number Amplification on Cloned Gene Expression and Growth of Recombinant Cell Cultures", Annals of the New York Academy of Sciences, 589, 111-120 (1990)

  35. Petti, T. F. and P. Dhurjati, "Object-Based Automated Fault Diagnosis", Chemical Engineering Communications, 102, 107-126 (1991)

  36. Tokatlidis, K., P. Dhurjati, J. Millet, P. Beguin and J-P. Aubert, "High Activity of Clostridium thermocellum endoglucanase D incorporated in inclusion bodies", FEBS Letters, 282,1, 205-208 (1991)

  37. Tokatlidis, K., S. Salamitou, P. BΘguin, P. Dhurjati, J-P. Aubert, "Interaction of the Duplicated Segment carried by Clostridium thermocellum cellulases with cellulose components", FEBS Letters, 291, 2, 185-188 (1991)

  38. Petti, T. F. and P. Dhurjati, "A Coupled Knowledge Based System Using Fuzzy Optimization for Advisory Control", AICHE J, 38, 1369-1378 (1992)

  39. Tokatlidis, K., S. Salamitou, T. Fujino, P. Béguin, P. Dhurjati, J. Millet, "Duplicated segment of clostridium thermocellum cellulases", in Protein Folding: In vivo and In Vitro, edited by Jeffrey L. Cleland (ACS Symposium Series 526 1993)

  40. Klein, J. H. and P. Dhurjati, "Experimental Investigation of the in vivo Kinetics of Inclusion Body Formation", in Protein Folding: In vivo and In Vitro, edited by Jeffrey L. Cleland (ACS Symposium Series 526 1993)

  41. Petti, T. F. and P. Dhurjati, "On-Line Hydrogen Resource Management in a Refinery Using Fuzzy Optimization", in On-Line Fault Detection and Supervision in the Chemical Process Industries, edited by P. Dhurjati and G. Stephanopoulos (Pergamon Press 1993)

  42. Pillai, V., A. Beris and P. Dhurjati, "Novel Method for the Optimal Control of Batch Processes", in On-Line Fault Detection and Supervision in the Chemical Process Industries, edited by P. Dhurjati and G. Stephanopoulos (Pergamon Press 1993)

  43. Gaertner, J. G. and P. Dhurjati, "Fractional Factorial Study of Hybridoma Behavior: I. Kinetics of Growth and Antibody Production", Biotechnology Progress, 9, 298-308 (1993)

  44. Gaertner, J. G. and P. Dhurjati, "Fractional Factorial Study of Hybridoma Behavior: II. Kinetics of Nutrient Uptake and Waste Production", Biotechnology Progress, 9, 309-316 (1993)

  45. Gaertner, J. G. and P. Dhurjati, "Specific cell adhesion as potential cause of interactions between hybridoma cells and reactor surfaces", Biotechnology Letters, 15(8), 803-808 (1993)

  46. Leipold, R. J. and P. Dhurjati, "Construction and Characterization of a Specialized Ribosome System for the Overproduction of Proteins in E. Coli", Biotechnology Progress, 8, 345-354 (1993)

  47. Kordon, A., R. Pitchumani, A. Beris, V. M. Karbhari and P. Dhurjati, "A Rheological Model for Particulate Ceramic Slurries at Low Temperatures", Scripta METTALURGICA et MATERIALIA, 29, 1095-1099 (1993)

  48. Leipold, R. J. and P. Dhurjati, "Review: Specialized Ribosomes in Escherichia coli", Biotechnology Progress, 9, 443-449 (1993)

  49. Konstantin, K. B., P. Dhurjati, T. Van dyk, W. Majarian, R. Larossa, "Real-time Compensation of the Inner Filter Effect in High-Density Bioluminescent Cultures", Biotechnology and Bioengineering, 42, 1190-1198 (1993)

  50. Tokatlidis, K., P. Dhurjati and P. Béguin, "Properties conferred on Clostridium thermocellum endoglucanase celC by grafting the duplicated segment of endoglucanase celD", Protein Engineering, 6, 947-952 (1993)

  51. Kordon, A. K., A. N. Beris, P. S. Dhurjati, B. Rossing and W. B. Johnson, "A knowledge base system architecture for a rapid ceramic performing process", Int. SAMPE Tech Conf., 25, 692-701 (1993)

  52. Pillai, V., P. Dhurjati and A. Beris, "Intelligent Control of an Autoclave Cure Process using an Expert System", Adv. Instrum. Control, 48, 48, 1431-1441 (1993)

  53. Leipold, R. J., C. E. Krewson and P. Dhurjati, "Mathematical Model of Temperature-Sensitive Plasmid Replication", Plasmid, 32, 131-167 (1994)

  54. Pillai, V., A. Beris and P. Dhurjati, "Implementation of model-based optimal temperature profiles for autoclave curing of composites using a knowledge-based system", Industrial and Engineering Chemistry Research, 33, 2443-2452 (1994)

  55. Van Dyk, Tina K., W. R. Majarian, K. B. Konstantinov, R. M. Young, P. Dhurjati and R. LaRossa, "Rapid and sensitive pollutant detection by induction of heat shock gene-bioluminescence gene fusions", Applied and Environmental Microbiology, 60, 1414-1420 (1994)

  56. Pitchumani, R., A. K. Kordon, A. N. Beris, V. M. Karbhari, P. S. Dhurjati, B. R. .Rossing and W. B. Johnson, "Thermofluid analysis and design of a low-temperature performing process", Metall. Mater. Trans. B, 25b, 761-771 (1994)

  57. Leipold, R. J., R. W. Morgan and P. Dhurjati, "Synthesis of non-translating or translating specialized ribosomes causes feedback regulation of ribosomal RNA synthesis in Escherichia coli", Biochemical and Biophysical Research Communications, 206, 393-400 (1995)

  58. Klein, J. and P. Dhurjati, "Protein Aggregation Kinetics in Escherichia coli Overexpressing a Salmonella typhimurium Che Y Mutant", Applied and Environmental Microbiology, 61, 1220-1225 (1995)

  59. Kordon, A. and P. Dhurjati, "An Expert System for Crude Unit Process Supervision", Proc.3rd IFAC Symp. on On-line Fault Detection & Supervision in the Chemic, 35-39 (1995)

  60. Pillai, V., A. Beris and P. Dhurjati, "Heuristics Guided Optimization of a Batch Autoclave Curing Process", Computers and Chemical Engineering, 20, 275-294 (1996)

  61. Rupani, S., Konstantin, K.B., M. B. Gu, P. Dhurjati, T. Van Dyk and R. LaRossa, "Characterization of the stress response of a bioluminescent biological sensor in batch and continuous cultures", Biotech. Progress, 12, 387-392 (1996)

  62. Gu, Man Bock, P. Dhurjati, T. Van Dyk and R. LaRossa, "A Novel Miniature Bioreactor for Sensing Toxicity using Recombinant Bioluminescent Escherichia coli cells", Biotech. Progress, 12, 393-397 (1996)

  63. Gu, Zhengrong, Harry Lam and P. Dhurjati, "Feature Correlation Method for Enhancing Fermentation Development: A Comparison of Quyadratic Regression with Artificial Neural Networds", Computers and Chemical Engineering, 20, S407-S412 (1996)

  64. Kordon, A. K., P. Dhurjati and B.J. Bockrath, "On-line Expert System for Odor Complaints in a Refinery", Computers and Chemical Engineering, 20, S1449-S1454 (1996)

  65. Brendel, R. J., B. A. Ogunnaike and P. Dhurjati, "A Nonlinear PI Controller Based on a Low-Order Empirical Process Model", Proc. IEEE on Computer-Aided Control System Design, 292-296 (1996)

  66. Pillai, V., A. Beris and P. Dhurjati, "Intelligent Curing of Thick Composites using a Knowledge Based System", Journal of Composite Materials, 31, 22-51 (1997)

  67. D. J. Michaud, A.N. Beris, P. Dhurjati, "Curing Behavior of Thick-Sectioned RTM Composites", Journal of Composite Materials, 32, 1273-1296 (1998)

  68. T. English, L. Kaiser, F. Doyle, P. Dhurjati, "Analysis of Post-upset Plant Data for Fault Detection", in On-Line Fault Detection and Supervision in the Chemical Process Industries, edited by P. Dhurjati and S. Cauvin (Pergamon Press, Oxford 1998)

  69. P. Dhurjati, "Reconciling Academic Approaches and Industrial Realities: Lessons from Fault Diagnosis Applications", in On-Line Fault Detection and Supervision in the Chemical Process Industries, edited by P. Dhurjati and S. Cauvin (Pergamon Press, Oxford 1998)

  70. Oh, J-T, T. K. Van Dyk, Y. Cajal, P. Dhurjati, M. Sasser, M. K. Jain, "Osmotic Stress in Viable Escherichia coli as the basis for Antibiotic Response by Polymyxnin B", Biochemical and Biophysical Research Communications, 246, 619-623 (1998)

  71. Oh, J-T, Y. Cajal, P. Dhurjati, T. K. Van Dyk, M. K. Jain, "Cecropins induce the hyperosmotic stress response in Escherichia coli", Biochimica et Biophysica Acta, 1415, 235-245 (1998)

  72. P. Dhurjati and Sylvie Cauvin, "On-line Fault Detection and Supervision in the Chemical Process Industries", Control Engineering Practice, 7, 7, 863-864 (1999)

  73. Kordon, A., P. Dhurjati, Y.O. Fuentes, B.A. Ogunnaike, "An Intelligent Parallel Control System Structure for Plants with Multiple Operating Regimes", Journal of Process Control, 453-460 (1999)

  74. Chen Z.C, Nora C. Beck-Tan, P. Dhurjati, T. K. van Dyk, R. A. LaRossa, S. L. Cooper, "Quaternary Ammonium Functionalized Poly (propylene imine) Dendrimers as Effective Antimicrobials: Structure-Activity Studies", Biomacromolecules, 1, 473-480 (2000) Full Text PDF

  75. Trezzani, I., Nadri, M., Hammouri, H., Lieto, J., Dorel, C., Lejeune, P., Dhurjati, P., Bellalou, J., Longin, R, "Quantification en ligne de al synthèse de molécules recombinantes par mesure de bioluminescence", Récents Progrès en Génie des Procédés, 15 (87), 147-155 (2001) Full Text PDF Not Available Online

  76. Michaud, D.J., A.N. Beris and P.S. Dhurjati, "Thick-sectioned RTM composite manufacturing: Part I. In situ cure model parameter identification and sensing", Journal of Composite Materials, 36 (10), 1175-1200 (2002) Full Text PDF

  77. Michaud, D.J., A.N. Beris and P.S. Dhurjati, "Thick-sectioned RTM composite manufacturing: Part II. Robust cure cycle optimization and control", Journal of Composite Materials, 36, 1201-1231 (2002) Full Text PDF

  78. Kauffman, K.J., E. M. Pridgen, F. J. Doyle, III, P. S. Dhurjati, A. S. Robinson, "Decreased protein expression and intermittent recoveries in BiP levels result from cellular stress during heterologous protein expression in Saccharomyces cerevisiae", Biotechnol. Prog., 18, 942-950 (2002) Full Text PDF

  79. Michaud, D. J., A. G. Marsh, and P. S. Dhurjati, "eXPatGen: Generating dynamic expression patterns for the systematic evaluation of analytical methods", Bioinformatics, 19(9), 1140-1146 (2003) www.che.udel.edu/eXPatGen/ Full Text PDF

  80. R. Lall, R. Mutharasan, Y. T. Shah, P. S. Dhurjati, "Decolorization of the dye Reactive Blue 19, using ozonation, ultrasound and ultrasound-enhanced ozonation", Water Environmental Research, 75, 171-179 (2003) Full Text PDF Not Available Online

  81. Trezzani, I., Nadri, M., Dorel, C., Lejeune, P., Bellalou, J., Lieto, J., Hammouri, H., Lieto, Longin, R., Dhurjati, P., "Monitoring of recombinant protein production using bioluminescence in a semi-automated fermentation process", Biotechnology Progress, 19, 1377-1382 (2003) Full Text PDF

  82. R. J. Brendel, B. A. Ogunnaike, P. S. Dhurjati, "Nonlinear PI Controllers Based on Low-Order Empirical Process Models", IEC Research, 42, 4668-4677 (2003) Full Text PDF

  83. R. Lall, G. Gao, P. Dhurjati, J. Edwards, "MRAD: Metabolic Reaction Analysis Database - An Entity-Relationship Approach", Journal of Molecular Microbiology and Biotechnology, 6 (1) (2003) http://capb.dbi.udel.edu/whisler/

  84. P. Dufour, S. Bhartiya, P. S. Dhurjati, F. J. Doyle III, "Neural Network-based Software Sensor: Training Set Design and Application to a Continuous Pulp Digester", Control Engineering Practice (2004), In Press

  85. V. Agrawal, C. Zhang, A.D. Shapiro and P.S. Dhurjati, "A Dynamic Mathematical Model to Clarify Signaling Circuitry Underlying Programmed Cell Death Control in Arabidopsis Disease Resistance", Biotechnology Progress, 20, 426-442 (2004) http://systemsbiology.udel.edu/ Full Text PDF

  86. P. Dufour, D.J. Michaud, Y. Toure, P.S. Dhurjati, "A Partial Differential Equation Model Predictive Control Strategy: Application to Autoclave Composite Processing", Computers and Chemical Engineering, 28, 545-556 (2004) Full Text PDF

  87. M. Nadri, I. Trezzani, H. Hammouri, P. Dhurjati, R. Longin, J. Lieto, "Modeling and Observer Design for Recombinant Escherichia coli strain", Bio Process Engineering, Submitted